08-09 October 2025

Vaccines at a Crossroads: Precision Vaccinology as a New Paradigm

Day 1: 08 October 2025

08:00 – 08:30 am

Registration: Main Lobby, Hotel Champlain

08:30 – 08:50 am

Welcome: Ofer Levy, MD, PhD (Precision Vaccines Program, Boston Children’s Hospital & Harvard Medical School)

08:50 – 09:35 am

Keynote Speaker: John Tsang, PhD, MMath (Yale University)

09:35 – 10:00 am

Coffee Break

Session 1: Emerging And Re-Emerging Diseases And Challenges

10:00 – 10:15 am

RSV Prevention Strategies: An Example Of Precision Vaccinology, Bukky Idoko, PhD (Sanofi)

10:15 – 10:30 am

Updates on Dengue Vaccines, Beth Kirkpatrick, MD (University of Vermont)

10:30 – 10:45 am

Large-Scale Antibody Reactome Profiling Identifies Herpesvirus-Autoantigen Associations Underlying Chronic Disease, Jessica Lasky-Su, DSc, MS (Brigham and Women’s Hospital)

10:45 – 11:00 am

Q&A Panel

Session 2: Preclinical Modeling Of Vaccine Action

11:00 – 11:15 am

Unlocking Immunity: The Adjuvant AS01 As A Key To Vaccinate Diverse Populations, Margherita Coccia, DPhil (GlaxoSmithKline)

11:15 – 11:30 am

Deep Phenomics Of Human Innate And Adaptive Responses, Soumik Barman, PhD (Precision Vaccines Program, Boston Children’s Hospital & Harvard Medical School)

11:30 – 11:45 am

Guzman Sanchez-Schmitz, PhD (Precision Vaccines Program, Boston Children’s Hospital & Harvard Medical School)

11:45 – 12:00 pm

Mining The CD4 Antigen Repertoire Or Next-Generation Tuberculosis Vaccines, Dan Barouch, MD, PhD (Beth Israel Deaconess Medical Center & Harvard Medical School)

12:00 – 12:15 pm

Q&A Panel

12:15 – 01:45 pm

Free time to explore Burlington and enjoy lunch at your leisure.

Session 3: Vaccine Safety

02:00 – 02:15 pm

Immunization Safety: From Risk Assessment To Risk Reduction, Robert Chen, MD (Brighton Collaboration & INSIS)

02:15 – 02:30 pm

International Network Of Special Immunization Services: Harnessing Precision Vaccinology To Advance Vaccine Safety Science, Karina Top, MD (University of Alberta & INSIS)

02:30 – 02:45 pm

Vaccine Safety: Assessing And Communicating Risks, Al Ozonoff, PhD (Broad Institute at Massachusetts Institute of Technology & Boston Children’s Hospital)

02:45 – 03:00 pm

Q&A Panel

Session 4: Systems Vaccinology

03:00 – 03:15 pm

The Immune Signatures Data Resource: An AI-Ready Compendium of Systems Vaccinology Datasets, Joann Arce, PhD (Precision Vaccines Program, Boston Children’s Hospital & Harvard Medical School)

03:15 – 03:30 pm

Sean Diehl (University of Vermont)

03:30 – 03:45 pm

Casey Shannon (University of British Columbia)

03:45 – 04:00 pm

Q&A Panel

04:00 – 04:35 pm

Oral Abstract Presentations

04:35 – 04:45 pm

Closing Remarks

05:15 – 05:20 pm

Meet In Lobby To Walk To Dinner

05:30 – 07:30 pm

Dinner on the Spirit of Ethan Allen Cruise

Day 2: 09 October 2025

08:00 – 08:05 am

Opening Remarks

08:05 – 08:50 am

Keynote Speaker: Paolo Palma (Ospedale Pediatrico Bambino Gesu & Vaccinopolis), Pediatric HIV And The Search For An Effective Immunotherapeutic Strategy

Session 5: Clinical Vaccinology

08:50 – 09:05 am

Age-Specific Trained Immunity, Asimenia Angelidou, MD, PhD (Precision Vaccines Program, Boston Children’s Hospital & Harvard Medical School, Beth Israel Deaconess Medical Center)

09:05 – 09:20 am

Dengue Vaccines, Kristen Pierce, MD (University of Vermont)

09:20 – 09:35 am

Systems Biology To Define Biomarkers Of The Reactogenicity And Immunogenicity Of GLA-SE Adjuvanted Gp120 HIV Vaccine In Infants, Kinga Smolen, PhD (Precision Vaccines Program, Boston Children’s Hospital & Harvard Medical School)

09:35 – 09:50 am

Q&A Panel

09:50 – 10:50 am

Coffee Break, Poster Presentations, and Exhibits

Session 6: Implications Of Climate And Population Trajectory On Precision Vaccinology

10:50 – 11:05 am

Nelly Ameyogbe, PhD (University of British Columbia)

11:05 – 11:20 am

Aging And Vaccinology, Amy Sherman, MD (Brigham And Women’s Hospital)

11:20 – 11:35 am

Lindsey Baden, MD (Brigham And Women’s Hospital)

11:35 – 11:50 am

Q&A Panel

12:00 – 03:00 pm

Free time to explore Burlington and enjoy lunch at your leisure.

03:00 – 04:00 pm

Panel Discussion: Vaccines At A Crossroads: Considerations & Path Forward

  • Moderator: Lindsey Baden, MD (Brigham and Women’s Hospital)
  • Jay Evans, PhD (Inimmune Inc)
  • Ofer Levy, MD, PhD (Precision Vaccines Program, Boston Children’s Hospital & Harvard Medical School)
  • Martin Kulldorff, PhD (CDC Advisory Committee On Immunization Practices)
  • Christine Benn, MD, PhD (University Of Southern Denmark)
  • Session 7: Adjuvants

    04:00 – 04:15 pm

    Human In Vitro Modeling Platforms For The Preclinical Investigation Of Adjuvant Combinations, Simon Van Haren, PhD (Precision Vaccines Program, Boston Children’s Hospital & Harvard Medical School)

    04:15 – 04:30 pm

    Adjuvant Centric Vaccinology, David Dowling, PhD (Precision Vaccines Program, Boston Children’s Hospital & Harvard Medical School)

    04:30 – 04:45 pm

    Margie Ackerman, PhD (Dartmouth University)

    04:45 – 05:00 pm

    Adjuvants: Bridging The Gap Between Innate And Adaptive Immunity, Jay Evans, PhD (Inimmune Inc)

    05:00 – 05:15 pm

    Q&A Panel

    Session 8: Addressing The Opioid Epidemic With Vaccines

    05:15 – 05:30 pm

    Youth Opioid Epidemic, Sharon Levy, MD, MPH (Boston Children’s Hospital & Harvard Medical School)

    05:30 – 05:45 pm

    Attitudes Towards An Opioid Vaccine, Elissa Weitzman, ScD, MSc (Boston Children’s Hospital)

    05:45 – 06:00 pm

    Mucosal Vaccine Protection Against Fentanyl Intoxication Generates Meningeal Plasma Cells and Requires IgA., Elizabeth "Betzi" Norton, PhD (Tulane University)

    06:00 – 06:15 pm

    Q&A Panel

    06:15 – 06:45 pm

    Oral Abstract Presentations

    06:45 – 07:00 pm

    Closing Remarks

    International Precision Vaccines Conference

    8 - 9 October 2025
    Hotel Champlain
    Burlington, Vermont, United States